Phentermine is a popular prescription medication used to help with weight loss, often prescribed for individuals struggling with obesity or overweight conditions. While its effectiveness in appetite suppression is well known, some users have reported a less-discussed side effect: hair loss. This leads many to ask, can phentermine cause hair loss?
In this article, we’ll explore the connection between phentermine and hair loss, the possible causes, how common it is, and what you can do if you’re experiencing hair thinning while taking this medication.
Phentermine is a prescription stimulant similar to an amphetamine. It works by suppressing appetite and increasing energy levels, making it easier for people to reduce calorie intake and lose weight. It’s often used short-term (usually 12 weeks or less) and may be part of a broader weight loss program that includes diet and exercise.
Phentermine is sold under various brand names, including Adipex-P, Lomaira, and Suprenza.
Hair loss is not listed as a common side effect of phentermine in FDA labeling or most clinical trials. However, many users report hair shedding during or after their course of treatment, which raises concern and confusion. So, while phentermine may not directly cause hair loss, there are several indirect factors that could explain this symptom.
If you’re experiencing hair thinning while taking phentermine, it may be due to one or more of the following reasons:
One of the most well-known triggers of hair loss is telogen effluvium, a temporary condition where hair prematurely enters the shedding phase of the growth cycle. This often happens 2–3 months after a significant stressor, such as rapid weight loss — which phentermine commonly causes.
Dramatic reductions in food intake can lead to vitamin and mineral deficiencies, particularly in iron, biotin, zinc, and protein — all of which are essential for hair growth. Even if you’re losing weight successfully, an imbalanced or low-calorie diet can impact hair health.
Phentermine is a stimulant, which can increase heart rate, raise cortisol levels, and impact sleep. These changes can be stressful for the body, which in turn may contribute to temporary hair loss.
Weight loss, medication, and stress can all influence hormonal balance, including thyroid function and sex hormones, both of which play roles in the hair growth cycle.
The good news is that hair loss from phentermine is usually temporary. If the cause is telogen effluvium or nutrient deficiency, hair typically regrows within 3–6 months once the triggering factor is removed and the body returns to balance.
However, if hair shedding continues long after stopping the medication or is accompanied by other symptoms (like scalp irritation or patchy hair loss), it may indicate a different issue that requires a dermatologist’s evaluation.
While official data is limited, user-reported side effects on forums, review sites, and social media suggest that hair loss is not uncommon, especially among those experiencing significant weight loss. However, because it’s often underreported in clinical trials, it’s difficult to determine exact prevalence.
If you’re taking phentermine and concerned about hair loss, here are some tips to help protect your hair health:
Ensure you’re eating a well-balanced diet rich in:
Consider a multivitamin supplement if you’re on a restricted calorie diet.
Dehydration can affect skin and hair health. Drink enough water to support your body’s metabolic changes during weight loss.
Incorporate stress-reducing activities like meditation, yoga, or regular walks. Reducing cortisol levels can help improve hair retention.
Give your hair a break from heat styling, chemical treatments, and tight hairstyles that can cause breakage.
If you notice excessive hair shedding, ask your healthcare provider to run tests for thyroid function, iron levels, and overall nutritional health. They may adjust your dosage or recommend supplements.
So, can phentermine cause hair loss? While phentermine is not directly linked to hair loss in medical literature, many people experience hair shedding due to rapid weight loss, poor nutrition, or bodily stress — all common during phentermine treatment.
Fortunately, this type of hair loss is usually temporary and reversible. By supporting your body with proper nutrition, managing stress, and consulting your healthcare provider, you can reduce the risk and support healthy hair growth during your weight loss journey.
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